PS 48
| CAS No. | 1180676-32-7 | Cat. No. | BCP08452 |
| Name | PS 48 | ||
| Synonyms | PS48;PS-48; | ||
| Formula | C17H15ClO2 | M. Wt | 286.75 |
| Description | PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PDK | ||
Structure
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