JW-55
| CAS No. | 664993-53-7 | Cat. No. | BCP08451 |
| Name | JW-55 | ||
| Synonyms | JW55;JW 55; | ||
| Formula | C25H26N2O5 | M. Wt | 434.48 |
| Description | JW 55 efficacy causes stabilization of Axin2 and it increases degradation of β-catenin signaling pathway. JW 55 also decreases canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. Wnt3a-induced HEK293 cells containing a transiently transfected ST-Luc (SuperTop-luciferase) reporter showed inhibition by JW55 with an IC50 value of 470 nM. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
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