Luseogliflozin
| CAS No. | 898537-18-3 | Cat. No. | BCP20937 |
| Name | Luseogliflozin | ||
| Synonyms | TS-71; TS 71; TS71; TS-071; TS 071; TS071; | ||
| Formula | C23H30O6S | M. Wt | 434.54 |
| Description | Luseogliflozin, also known as TS-71 and TS-071, is a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2 inhibitor). Luseogliflozin improves glycaemic control assessed by continuous glucose monitoring even on a low-carbohydrate diet. Luseogliflozin competitively inhibited human SGLT2 (hSGLT2)-mediated glucose uptake with a Ki value of 1.10 nM. In the absence of glucose, [(3)H]-luseogliflozin exhibited a high affinity for hSGLT2 with a Kd value of 1.3 nM. | ||
| Pathways | Ion Channel/Membrane Transporter GPCR/G Protein | ||
| Targets | SGLT | ||
Structure
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