GDC0834

  • Chemical Properties
CAS No. 1133432-49-1 Cat. No. BCP08433
Name GDC0834
Synonyms GDC-0837;GDC 0837;
Formula C33H36N6O3S M. Wt 596.74
  • Biological Activity
Description GDC-0834 is a small molecule inhibitor of Btk potentially useful in the treatment of RA and lymphoid malignancies. Administration of GDC-0834 (30 -- 100 mg/kg) in a rat CIA model induced a decrease of ankle swelling and reduction of morphologic pathology in a dose-dependent manner.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets BTK 

Structure

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