Gemfibrozil

  • Chemical Properties
CAS No. 25812-30-0 Cat. No. BCP08437
Name Gemfibrozil
Synonyms
Formula C15H22O3 M. Wt 250.33
  • Biological Activity
Description Gemfibrozil is a hyperlipidemic agent that elevates plasma HDL and lowers triglycerides and LDL by stabilizing apoA-I mRNA transcripts. It was found to inhibit inducible nitric oxide synthase by inhibiting the activation of nuclear factor-kappaB, activator protein-1 and CCAAT/enhancer-binding protein β.
Pathways Protease/Metabolic Enzyme Cell Cycle/DNA Damage 
Targets Cytochrome P450 PPAR 

Structure

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