AZ5104
| CAS No. | 1421373-98-9 | Cat. No. | BCP08428 |
| Name | AZ5104 | ||
| Synonyms | AZ-5104;AZ 5104;Demethylated AZ9291; metabolite of AZD9291; | ||
| Formula | C27H31N7O2 | M. Wt | 485.58 |
| Description | AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFR L858R/T790M, EGFR L858R, EGFR L861Q, EGFR and ErbB4, respectively. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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