米卡芬净
CAS号 | 235114-32-6 | 货号 | BCP20945 |
中文名 | 米卡芬净 | ||
英文名 | Micafungin | ||
中文别名 | |||
英文别名 | FK 463;FK463;FK-463;Mycamine; | ||
分子式 | C56H71N9O23S | 分子量 | 1270.27 |
生物活性 | Micafungin is a semi-synthetic echinocandin derived from a natural product of the fungus Coleophama empedri with potent antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. Inhibition of this enzyme weakens of the cell wall, thereby leading to osmotic lysis and eventually, fungal cell death. | ||
信号通路 | Microbiology/Virology | ||
靶 点 | Antifungal |
结构式
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