Abafungin
| CAS No. | 129639-79-8 | Cat. No. | BCP08353 |
| Name | Abafungin | ||
| Synonyms | BAY-W 6341;BAY-W-6341;BAY W 6341; | ||
| Formula | C21H22N4OS | M. Wt | 378.49 |
| Description | Like imidazole- and triazole-class antifungals, abafungin inhibits the fungal cytochrome P450 enzyme 14α-demethylase. This inhibition prevents the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane.In addition, abafungin inhibits the enzyme sterol 24-C-methyltransferase, modifying the composition of the fungal membrane.Abafungin has antibiotic activity against gram-positive bacteria as well as sporicidal activity.[ | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antifungal | ||
Structure
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