Acyclovir monophosphate

  • Chemical Properties
CAS No. 66341-16-0 Cat. No. BCP08348
Name Acyclovir monophosphate
Synonyms Acyclo-GMP;
Formula C8H12N5O6P M. Wt 305.18
  • Biological Activity
Description Acyclovir monophosphate is the monophosphate ester of Acyclovir. Acyclovir is an antiviral agent with activity against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and varicella zoster virus. Acyclovir is converted by a herpesvirus enzyme into acyclovir triphosphate that inhibits the synthesis of deoxyribonucleic acid (DNA) molecules in the virally infected cells, thereby inhibiting viral replication. It induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).
Pathways Microbiology/Virology 
Targets HSV 

Structure

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