MK-6892
| CAS No. | 917910-45-3 | Cat. No. | BCP20984 |
| Name | MK-6892 | ||
| Synonyms | MK 6892; MK6892; | ||
| Formula | C19H22N4O5 | M. Wt | 386.4 |
| Description | MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A. Ki and GTPγS EC50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively.MK-6892 is a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals. MK-6892 displays excellent receptor activity, good PK across species, remarkably clean off-target profiles, good ancillary pharmacology, and superior therapeutic window over niacin. | ||
| Pathways | Hormone Pathay GPCR/G Protein | ||
| Targets | GPR | ||
Structure
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