Rigosertib sodium
CAS No. | 592542-60-4 | Cat. No. | BCP08297 |
Name | Rigosertib sodium | ||
Synonyms | ON-01910 sodium; ON 01910 sodium; ON01910 sodium; | ||
Formula | C21H24NO8S. Na | M. Wt | 473.47 |
Description | Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | PLK |
Structure
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