LG100268
| CAS No. | 153559-76-3 | Cat. No. | BCP08283 |
| Name | LG100268 | ||
| Synonyms | LG 100268 ; LG-100268; | ||
| Formula | C24H29NO2 | M. Wt | 363.49 |
| Description | LG100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | RAR/RXR | ||
Structure
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