JIB-04
| CAS No. | 199596-05-9 | Cat. No. | BCP08265 |
| Name | JIB-04 | ||
| Synonyms | JIB04;JIB 04;NSC693627; | ||
| Formula | C17H13ClN4 | M. Wt | 308.76 |
| Description | JIB-04 induces transcriptional changes in a cancer-selective manner, including the downregulation of proliferative genes and the upregulation of the anti-proliferative/pro-apoptotic genes. JIB-04 blocks growth of lung and prostate cancer lines with IC50 as low as 10 nM, while produces less anti-proliferative activities on HBECs and PrSCs/PrECs. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Demethylase | ||
Structure
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