LMK-235
| CAS No. | 1418033-25-6 | Cat. No. | BCP08248 |
| Name | LMK-235 | ||
| Synonyms | LMK235;LMK 235; | ||
| Formula | C15H22N2O4 | M. Wt | 294.35 |
| Description | LMK-235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor. LMK-235 demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 = 0.49 and 0.32 μ M respectively). | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | HDAC | ||
Structure
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