LY 303511
| CAS No. | 154447-38-8 | Cat. No. | BCP08239 |
| Name | LY 303511 | ||
| Synonyms | LY303511;LY-303511; NV-128; NV 128; NV128; EM 101; EM-101; EM101; | ||
| Formula | C19H18N2O2 | M. Wt | 306.36 |
| Description | LY 303511 was first discovered as an inactive analog of LY294002 which does not inhibit PI 3-kinase, but recent research has shown LY 303511 to block cell proliferation via mTOR-dependent and independent mechanisms, without inducing apoptosis. LY 303511 has been shown to reduce G2M progression, G2M-specific cyclins and casein kinase 2 activity in A549 cells. It can be used as a negative control for the PI 3-kinase inhibitor LY294002. | ||
| Pathways | Ion Channel/Membrane Transporter Apoptosis Pathway PI3K/Akt/mTOR | ||
| Targets | Potassium Channel TNF Receptor mTOR | ||
Structure
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