Trelagliptin succinate

  • Chemical Properties
CAS No. 1029877-94-8 Cat. No. BCP08138
Name Trelagliptin succinate
Synonyms SYR-472 succinate; SYR472 succinate; SYR 472 succinate;
Formula C22H26FN5O6 M. Wt 475.47
  • Biological Activity
Description Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance.
Pathways Protease/Metabolic Enzyme 
Targets DPP 

Structure

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