4μ8C
  • Chemical Properties
CAS No. 14003-96-4 Cat. No. BCP21011
Name 4μ8C
Synonyms 4Mu8C; 4u8C;4U8C;IRE1 Inhibitor III;
Formula C11H8O4 M. Wt 204.18
  • Biological Activity
Description 4μ8C is a IRE1 Inhibitor. 4µ8C inhibits IRE1α splicing of Xbp1 mRNA (IC50 = 6.8 µM) and reduces subsequent gene expression of Erdj4 (IC50 = 3.4 µM) in stress-cultured MEF cells but does not block IRE1α autophosphorylation.

Structure

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