Idelalisib
| CAS No. | 1146702-54-6 | Cat. No. | BCP08088 |
| Name | Idelalisib | ||
| Synonyms | CAL101, GS-1101; GS 1101; GS1101; CAL-101; CAL 101; | ||
| Formula | C21H16FN7O | M. Wt | 401.41 |
| Description | Idelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and antineoplastic activities. CAL-101 inhibits the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K-delta is expressed primarily in hematopoietic lineages. The targeted inhibition of PI3K-delta is designed to | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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