Ertapenem Sodium

  • Chemical Properties
CAS No. 153773-82-1 Cat. No. BCP08022
Name Ertapenem Sodium
Synonyms MK 826; MK-826; MK826; MK-0826; MK 0826; MK0826; L 749345; L749345; L-749345; Invanoz; Invanz;
Formula C22H25N3O7S.Na M. Wt 497.5
  • Biological Activity
Description Ertapenem Sodium is the sodium salt of ertapenem, a 1-beta-methyl carbapenem and a broad-spectrum beta-lactam antibiotic with bactericidal activity. Ertapenem binds to penicillin binding proteins located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition of peptidoglycan synthesis results in weakening and lysis of the cell wall and cell death. Erapenem is resistant to hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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