Org 27569

  • Chemical Properties
CAS No. 868273-06-7 Cat. No. BCP08021
Name Org 27569
Synonyms Org27569; Org-27569;
Formula C24H28ClN3O M. Wt 409.95
  • Biological Activity
Description Org 27569 is a potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57).
Pathways GPCR/G Protein 
Targets Cannabinoid Receptor 

Structure

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