Erianin

Chemical Properties

CAS No.	95041-90-0	Cat. No.	BCP07974
Name	Erianin
Synonyms
Formula	C18H22O5	M. Wt	318.36

Biological Activity

Description	Erianin is a nature product extracted from Dendrobium chrysotoxum, having notable antitumour activity. Erianin inhibited endothelial metabolism in a JNK/SAPK-dependent manner. This mechanism may be involved in the potential antitumnor and antiangiogenic actions of Erianin. Erianin caused extensive tumour necrosis, growth delay and rapid vascular shutdown in hepatoma and melanoma models; it inhibited angiogenesis in vivo and in vitro and induced endothelial cytoskeletal disorganisation.

Description

Erianin is a nature product extracted from Dendrobium chrysotoxum, having notable antitumour activity. Erianin inhibited endothelial metabolism in a JNK/SAPK-dependent manner. This mechanism may be involved in the potential antitumnor and antiangiogenic actions of Erianin. Erianin caused extensive tumour necrosis, growth delay and rapid vascular shutdown in hepatoma and melanoma models; it inhibited angiogenesis in vivo and in vitro and induced endothelial cytoskeletal disorganisation.

Structure

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