TUG-770

  • Chemical Properties
CAS No. 1402601-82-4 Cat. No. BCP07966
Name TUG-770
Synonyms TUG 770; TUG770;
Formula C19H14FNO2 M. Wt 307.32
  • Biological Activity
Description TUG-770 is a highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist for treatment of type 2 diabetes. in vitro: TUG-770 (Compound 22) displayed excellent physicochemical and in vitro ADME properties, with good aqueous solubility, good chemical stability, low lipophilicity, and decreased plasma protein binding (PPB). TUG-770 furthermore showed excellent stability toward human liver microsomes (HLM), no inhibition of selected CYP-enzymes implicated in drug-drug interactions, no P-glycoprote
Pathways Hormone Pathay GPCR/G Protein 
Targets GPR 

Structure

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