Taranabant

  • Chemical Properties
CAS No. 701977-09-5 Cat. No. BCP21059
Name Taranabant
Synonyms MK 0364;MK 0364; MK0364;
Formula C27H25ClF3N3O2 M. Wt 515.96
  • Biological Activity
Description Taranabant, aslo known as MK-0364, a cannabinoid receptor type 1 inverse agonist being investigated as a potential treatment for obesity due to its anorectic effects. Taranabant reduces abdominal pain and increases intestinal transit in mice. It was discovered by Merck & Co. In October 2008, Merck has stopped its phase III clinical trials with the drugs due to high level of central side effects, mainly depression and anxiety.
Pathways GPCR/G Protein 
Targets Cannabinoid Receptor 

Structure

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