Moxonidine hydrochloride
| CAS No. | 75438-58-3 | Cat. No. | BCP07921 |
| Name | Moxonidine hydrochloride | ||
| Synonyms | Moxonidine HCl;BDF-5895 HCl;BDF5895 hydrochloride; | ||
| Formula | C9H13Cl2N5O | M. Wt | 280.15 |
| Description | Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.Moxonidine is a centrally acting antihypertensive drug that is selective agonist at the imidazoline receptor subtype 1 (I1). This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata. Moxonidine therefore causes a decrease in sympathetic nervous system activity and a decrease in blood pressure. Moxonidine may also promote sodium excretion, improve insulin resistance and glucose tolerance and protect against hypertensive target organ damage, such as kidney disease and cardiac hypertrophy. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Imidazoline Receptor | ||
Structure
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