Ansamitocin P-3

  • Chemical Properties
CAS No. 66584-72-3 Cat. No. BCP07918
Name Ansamitocin P-3
Synonyms Antibiotic C 15003P3; Maytansinol butyrate; C15003P3;Tam 330;NSC-292222;NSC 292222;NSC292222;
Formula C32H43ClN2O9 M. Wt 635.14
  • Biological Activity
Description Ansamitocin P-3 (AP-3) is an active and potent anti-tumor maytansinoid which is usually produced by Actinosynnema spp. Ansamitocin P-3 has shown potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. Ansamitocin P-3 is useful in synthesizing the anticancer drugs mertansine and emtansine.
Related Products 66547-09-9(Ansamitocin P-3')
Pathways Cell Cycle/DNA Damage Others Pathway 
Targets ADC Related Microtubule 

Structure

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