乙莫克舍
| CAS号 | 124083-20-1 | 货号 | BCP07911 |
| 中文名 | 乙莫克舍 | ||
| 英文名 | Etomoxir | ||
| 中文别名 | |||
| 英文别名 | (R)-(+)-Etomoxir; B 807-54; B807-54; B-807-54; B 80754; B80754; B-80754; | ||
| 分子式 | C17H23ClO4 | 分子量 | 326.82 |
| 生物活性 | Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPARα. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
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