Esomeprazole magnesium Dihydrate
| CAS No. | 217087-10-0 | Cat. No. | BCP07900 |
| Name | Esomeprazole magnesium Dihydrate | ||
| Synonyms | |||
| Formula | C34H36MgN6O6S2.2H2O | M. Wt | 749.16 |
| Description | Esomeprazole Magnesium is the magnesium salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulphenamide; the active sulphenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Proton Pump | ||
Structure
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