AR-A 014418

  • Chemical Properties
CAS No. 487021-52-3 Cat. No. BCP07893
Name AR-A 014418
Synonyms AR-AO 14418; AR 0133418; AR 014418; GSK 3β inhibitor;
Formula C12H12N4O4S M. Wt 308.31
  • Biological Activity
Description AR-A014418 is a effective GSK3 inhibitor with an IC 50 value of 104 +/- 27 nM. Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer's disease.
Pathways Wnt/Stem Cell PI3K/Akt/mTOR 
Targets GSK3 

Structure

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