EPI-743

  • Chemical Properties
CAS No. 1213269-98-7 Cat. No. BCP21072
Name EPI-743
Synonyms EPI 743;EPI743; Vatiquinone; alpha-Tocotrienol quinone;
Formula C29H44O3 M. Wt 440.66
  • Biological Activity
Description EPI 743 is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhancing the expression of genetic elements critical for cellular management of oxidative stress, and acting at the mitochondria to regulate electron transport.
Pathways Protease/Metabolic Enzyme 
Targets Mitochondrial Metabolism 

Structure

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