DBeQ
CAS No. | 177355-84-9 | Cat. No. | BCP07830 |
Name | DBeQ | ||
Synonyms | |||
Formula | C22H20N4 | M. Wt | 340.42 |
Description | Selective and reversible inhibitor of p97 ATPase (IC50 = 1.5 μM). Induces executioner caspases (caspase-3 and caspase-7) rapidly. Blocks the degradation of endoplasmic reticulum-associated degradation (ERAD) reporters; also blocks autophagosome maturation and promotes accumulation of LC3-II. | ||
Pathways | Ion Channel/Membrane Transporter Cell Cycle/DNA Damage | ||
Targets | ATPase p97 |
Structure
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