EPZ004777
| CAS No. | 1338466-77-5 | Cat. No. | BCP07821 |
| Name | EPZ004777 | ||
| Synonyms | EPZ 004777; EPZ-004777; | ||
| Formula | C28H41N7O4 | M. Wt | 539.67 |
| Description | EPZ004777 is a potent, selective inhibitor of DOT1L. Treatment of mixed lineage leukemia (MLL) cells with EPZ004777 selectively inhibits H3K79 methylation and blocks expression of leukemogenic genes. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Methyltransferase | ||
Structure
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