BAM7

  • Chemical Properties
CAS No. 331244-89-4 Cat. No. BCP07775
Name BAM7
Synonyms BAX Activator Molecule 7; BAM-7; BAM 7;
Formula C21H19N5O2S M. Wt 405.47
  • Biological Activity
Description Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts.
Pathways Apoptosis Pathway 
Targets Bcl2 

Structure

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