克拉夫定
| CAS号 | 163252-36-6 | 货号 | BCP21097 |
| 中文名 | 克拉夫定 | ||
| 英文名 | Clevudine | ||
| 中文别名 | |||
| 英文别名 | L-FMAU; L FMAU; LFMAU; | ||
| 分子式 | C10H13FN2O5 | 分子量 | 260.22 |
| 生物活性 | Clevudine, also known as L-FMAU, is an antiviral used in the treatment of Hepatitis B. Clevudine is differentiated from other oral agents by an unusual activation pathway to the biochemically active triphosphate, a mechanism of action of clevudine triphosphate that inhibits multiple steps of the hepatitis B virus (HBV) intracellular life cycle, a long half-life, and significant reduction of covalently closed circular DNA (cccDNA) in animal models. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | HBV | ||
结构式
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