P5091
| CAS No. | 882257-11-6 | Cat. No. | BCP07750 |
| Name | P5091 | ||
| Synonyms | P005091; Ethanone; P-005091; P 005091; P 5091; P-5091; | ||
| Formula | C12H7Cl2NO3S2 | M. Wt | 348.22 |
| Description | Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μM). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DUB | ||
Structure
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