伊格列净
| CAS号 | 761423-87-4 | 货号 | BCP07718 |
| 中文名 | 伊格列净 | ||
| 英文名 | Ipragliflozin | ||
| 中文别名 | |||
| 英文别名 | ASP1941; ASP-1941; ASP 1941; | ||
| 分子式 | C21H21FO5S | 分子量 | 404.45 |
| 生物活性 | Ipragliflozin, also known as ASP1941, is a potent and selective SGLT2 inhibitor for treatment of type 2 diabetes. Ipragliflozin treatment improved glycaemic control when added to metformin therapy and may be associated with weight loss and reductions in blood pressure compared to placebo. Ipragliflozin improves not only hyperglycemia but also diabetes/obesity-associated metabolic abnormalities in type 2 diabetic mice. It was approved for use in Japan in 2014. | ||
| 信号通路 | Ion Channel/Membrane Transporter GPCR/G Protein | ||
| 靶 点 | SGLT | ||
结构式
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