Pretomanid
| CAS No. | 187235-37-6 | Cat. No. | BCP21111 |
| Name | Pretomanid | ||
| Synonyms | PA824; PA 824;PA-824; | ||
| Formula | C14H12F3N3O5 | M. Wt | 359.26 |
| Description | PA-824 is an experimental anti-tuberculosis drug and one of two nitroimidazoles in phase II clinical trials to treat tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). The activity of PA-824 against M. tuberculosis was also assessed grown under conditions of oxygen depletion. PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
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Genetic and Virulence Characteristics of Linezolid and Pretomanid Dual Drug-Resistant Strains Induced from Mycobacterium tuberculosis in vitro
Publications Citing of Biochempartner's Pretomanid(CAS:187235-37-6) |
Structure
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