GSK2578215A
| CAS No. | 1285515-21-0 | Cat. No. | BCP07701 |
| Name | GSK2578215A | ||
| Synonyms | GSK2578215-A; GSK2578215 A; | ||
| Formula | C24H18FN3O2 | M. Wt | 399.42 |
| Description | Potent leucine-rich repeat kinase 2 (LRRK2) inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 against a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant. | ||
| Pathways | Others Pathway | ||
| Targets | LRRK2 | ||
Structure
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