AVL-292
CAS No. | 1202757-89-8 | Cat. No. | BCP07702 |
Name | AVL-292 | ||
Synonyms | LMK-235; LMK235; AVL292; AVL 292; | ||
Formula | C22H22FN5O3 | M. Wt | 423.44 |
Description | AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk currently being evaluated in a Phase 1b clinical trial in relapsed, refractory B cell malignancies including Chronic Lymphocytic Leukemia (CLL) and non-Hodgkin lymphomas. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Cell Cycle/DNA Damage Epigenetics | ||
Targets | HDAC BTK |
Structure
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