AVL-292

  • Chemical Properties
CAS No. 1202757-89-8 Cat. No. BCP07702
Name AVL-292
Synonyms LMK-235; LMK235; AVL292; AVL 292;
Formula C22H22FN5O3 M. Wt 423.44
  • Biological Activity
Description AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk currently being evaluated in a Phase 1b clinical trial in relapsed, refractory B cell malignancies including Chronic Lymphocytic Leukemia (CLL) and non-Hodgkin lymphomas.
Pathways Angiogenesis/Protein Tyrosine Kinase Cell Cycle/DNA Damage Epigenetics 
Targets HDAC BTK 

Structure

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