Pixantrone Maleate
| CAS No. | 144675-97-8 | Cat. No. | BCP07678 |
| Name | Pixantrone Maleate | ||
| Synonyms | BBR 2778; BBR2778; BBR-2778; Pixantrone; | ||
| Formula | C17H19N5O2.2(C4H4O4) | M. Wt | 441.44 |
| Description | Pixantrone dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.