TDZD-8
| CAS No. | 327036-89-5 | Cat. No. | BCP07657 |
| Name | TDZD-8 | ||
| Synonyms | GSK-3β Inhibitor I; NP01139;TDZD8; TDZD 8; NP 01139; NP-01139;GSK-3beta Inhibitor I; | ||
| Formula | C10H10N2O2S | M. Wt | 222.26 |
| Description | TDZD-8 is a selective inhibitor of GSK-3, a thiadiazolidinone derivative, non-ATP competitive inhibitor of GSK-3β (IC50 = 2 μM). It does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. TDZD-8 has been proposed to bind to the kinase site of GSK-3β. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 | ||
Structure
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