Dynasore
CAS No. | 304448-55-3 | Cat. No. | BCP07648 |
Name | Dynasore | ||
Synonyms | LM-8047; LM8047; | ||
Formula | C18H14N2O4H2O | M. Wt | 322.31 |
Description | Dynasore is a dynamin inhibitor (IC50 = 15 μM). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages. | ||
Pathways | Others Pathway | ||
Targets | Dynamin |
Structure
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