Dynasore

  • Chemical Properties
CAS No. 304448-55-3 Cat. No. BCP07648
Name Dynasore
Synonyms LM-8047; LM8047;
Formula C18H14N2O4H2O M. Wt 322.31
  • Biological Activity
Description Dynasore is a dynamin inhibitor (IC50 = 15 μM). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.
Pathways Others Pathway 
Targets Dynamin 

Structure

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