PP1

  • Chemical Properties
CAS No. 172889-26-8 Cat. No. BCP07604
Name PP1
Synonyms AGL 1872; EI 275; PP 1; PP-1;
Formula C16H19N5 M. Wt 281.36
  • Biological Activity
Description PP1(AGL1872) is a Src family kinase,inhibitor. PP1/AGL1872 potently inhibited recombinant p60c-src in vitro and Src-dependent tyrosine phosphorylation in p60c-srcF572-transformed NIH3T3 cells. PP1/AGL1872 also potently inhibited PDGF-stimulated migration of HCASMCs.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Src/Bcr Abl 

Structure

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