PFI-1
| CAS No. | 1403764-72-6 | Cat. No. | BCP07505 |
| Name | PFI-1 | ||
| Synonyms | PF-06405761; PFI 1; PFI1; | ||
| Formula | C16H17N3O4S | M. Wt | 347.39 |
| Description | PFI-1 can efficiently block the interaction of BET BRDs with H3 and H4 acetylated histone tails. Inhibition of the BET-histone interaction results in transcriptional downregulation of a number of oncogenes, providing a novel pharmacologic strategy for the treatment of cancer. | ||
| Pathways | Epigenetics | ||
| Targets | Epigenetic Reader Domain | ||
Structure
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