NSC 66811
| CAS No. | 6964-62-1 | Cat. No. | BCP07490 |
| Name | NSC 66811 | ||
| Synonyms | NSC-66811; NSC66811; | ||
| Formula | C23H20N2O | M. Wt | 340.42 |
| Description | Potent MDM2 inhibitor (Ki = 120 nM) which disrupts MDM2-p53 interaction and activates p53 function. Induces p21, p53 and MDM2 accumulation in human colon cancer cells in vitro. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Mdm2 p53 | ||
Structure
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