Inolitazone
| CAS No. | 223132-37-4 | Cat. No. | BCP07478 |
| Name | Inolitazone | ||
| Synonyms | Efatutazone; CS-7017; RS5444;CS7017; RS-5444;CS 7017; RS 5444; | ||
| Formula | C27H26N4O4S | M. Wt | 502.58 |
| Description | Inolitazone, also know as CS-7017, RS5444 and Efatutazone , is an orally bioavailable PAPR-gamma inhibitor with potential antineoplastic activity. Inolitazone binds to and activates peroxisome proliferation-activated receptor gamma (PPAR-gamma), which may result in the induction of tumor cell differentiation and apoptosis, and so a reduction in tumor cell proliferation. PPAR-gamma is a nuclear hormone receptor and ligand-activated transcription factor controlling gene expression involved in such cellular processes as differentiation, apoptosis, cell-cycle control, carcinogenesis, and inflammation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PPAR | ||
Structure
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