Fexinidazole
| CAS No. | 59729-37-2 | Cat. No. | BCP07460 |
| Name | Fexinidazole | ||
| Synonyms | Hoe-239; Hoe 239; Hoe239; | ||
| Formula | C12H13N3O3S | M. Wt | 279.32 |
| Description | Fexinidazole, also known as Hoe-239, antiparasitic agent potentially for the treatment of trypanosomiasis and leishmaniasis. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologically relevant active metabolites in vivo are the sulfoxide and sulfone. Fexinidazole is the first drug candidate for the treatment of advanced-stage sleeping sickness in thirty years. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antiparasitics | ||
Structure
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