Sotagliflozin

  • Chemical Properties
CAS No. 1018899-04-1 Cat. No. BCP07416
Name Sotagliflozin
Synonyms LX-4211; LX 4211;LX4211;
Formula C21H25ClO5S M. Wt 424.94
  • Biological Activity
Description Sotagliflozin, also known as LX4211, is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose. Sotagliflozin is currently being developed by Lexicon for the treatment of type 1 and type 2 diabetes mellitus. Sotagliflozin may be an effective and promising medication for treating not only Type 2 diabetes (the common target for non-insulin medications for diabetes), but also Type 1 as well.
Pathways Ion Channel/Membrane Transporter GPCR/G Protein 
Targets SGLT 

Structure

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