米铂一水合物

  • 化学数据
CAS号 250159-48-9 货号 BCP07401
中文名 米铂一水合物
英文名 Miriplatin hydrate
中文别名 米铂水合物;
英文别名 SM-11355; SM 11355; SM11355; Miripla; Miriplatin; MTP;
分子式 C34H68N2O4Pt.H2O 分子量 782.02
  • 用途
生物活性 Miriplatin (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin is a lipophilic platinum complex that can be easily suspended in Lipiodol and gradually releases active platinum compounds in tumor tissue. Miriplatin is less severe toxicity profile compared to other platinum anticancer agents.Miriplatin was approved for lipiodolization for the treatment of hepatocellular carcinoma in 2009. It is a lipophilic platinum complex containing myristates as leaving groups, and can be easily suspended in ethyl esters of iodized fatty acids obtained from poppy seed oil.
信号通路 Cell Cycle/DNA Damage 
靶 点 DNA Alkylator/Crosslinker 

结构式

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