AMG-517

  • Chemical Properties
CAS No. 659730-32-2 Cat. No. BCP07380
Name AMG-517
Synonyms AMG517; AMG 517;
Formula C20H13F3N4O2S M. Wt 430.4
  • Biological Activity
Description The vanilloid receptor TRPV1 has been identified as a molecular target for the treatment of pain associated with inflammatory diseases and cancer. AMG 517 is a potent and selective transient receptor potential vanilloid-1 (TRPV1) antagonist. AMG 517 was selected as a second-generation candidate for further evaluation in human clinical trials as a potential new treatment for chronic pain.
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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