AMG-517
CAS No. | 659730-32-2 | Cat. No. | BCP07380 |
Name | AMG-517 | ||
Synonyms | AMG517; AMG 517; | ||
Formula | C20H13F3N4O2S | M. Wt | 430.4 |
Description | The vanilloid receptor TRPV1 has been identified as a molecular target for the treatment of pain associated with inflammatory diseases and cancer. AMG 517 is a potent and selective transient receptor potential vanilloid-1 (TRPV1) antagonist. AMG 517 was selected as a second-generation candidate for further evaluation in human clinical trials as a potential new treatment for chronic pain. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | TRP Channel |
Structure
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