Cilengitide
CAS No. | 188968-51-6 | Cat. No. | BCP07359 |
Name | Cilengitide | ||
Synonyms | EMD121974;EMD 121974;EMD-121974;NSC-707544;NSC 707544;NSC707544; | ||
Formula | C27H40N8O7 | M. Wt | 588.66 |
Description | Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | Integrin |
Structure
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